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Green Tea Catechins: Cancer Protection

May 5, 2012

Jin et al, investigated the effects of (-)-epigallocatechin-3-gallate (EGCG), an active compound in green tea, on hepatocellular carcinoma (HCC) cells.

Results showed that EGCG significantly inhibited the viability and migration of cancer cells. EGCG also significantly inhibited the prostaglandin production. In previous studies blockade of prostaglandin synthesis in vitro or in vivo results in inhibition of tumor growth.

In conclusion, these findings suggest that the anti-cancer effects in liver cells of Green Tea catechins might be mediated, at least partially, through the suppressing of various receptor expression and prostaglandin production.

Green tea is used as a base in CALM&RELAX, YOUNG&FUN, UP&GO and SLIM&FIT.

Further Reading:

Thakur et al, findings indicate that Green Tea polyphenols (EGCG) causes acetylation of p53 by inhibiting class I HDACs, a function that is likely to be part of the mechanisms that control the physiological activity of p53 which is associated with cancer cycle arrest and Apoptosis.

Karmall et al, Review: prostaglandins and cancer. Blockade of prostaglandin synthesis in vitro or in vivo results in inhibition of tumor growth. Involvement of prostaglandins is implicated in the actions of tumor promoters.

 

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