Skip to content

Anti-inflammatory activities of Cinnamon Extract

December 5, 2012

Cinnamon, as we know from the pages on this website and the InnOrbit product page, is a popular ingredients for traditional medicines like Ayurveda and has various pharmacological activities which include anti-viral, and anti-cancer properties amongst others.  In a study by Hong et al the in vivo and in vitro inhibitory effect of Cinnamon water extract on induced tumor necrosis factor (TNF)-alpha and its underlying intracellular mechanisms was investigated in an animal model system.

Cinnamon extract were administrated and serum levels of TNF-alpha and interleukin (IL)-6 were determined 1 hour after Lipopolysaccharide stimulation.  Various biomarkers were assayed for viability, cytokine expression and signaling molecules upon stimulation.  Liposaccharides act as endotoxins and elicit strong immune responses in animals.

RESULTS:

The results show that oral administration of cinnamon in an animal model system significantly decreased the serum levels of TNF-alpha and IL-6. CWE treatment in vitro decreased the mRNA expression of TNF-alpha. The scientist conclude that treatment with cinnamon extract decreased LPS-induced TNF-alpha in serum and the results indicate that the observed anti-inflammatory action of Cinnamon extract may originate from the presence of polyphenols.

About these ads
No comments yet

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

Follow

Get every new post delivered to your Inbox.

Join 57 other followers

%d bloggers like this: