Neuroprotective effects of Mint Compound
July 8, 2011
Linarin, a natural occurring flavanol from Mint (Mentha arvensis) is known to have anti-acetylcholinesterase effects.
Acetylcholinesterase is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is part of the system that transmits nerve signals.
A study by Lou et al explored the neuroprotective effects of linarin against neurotoxicity in an animal model.
The results showed that linarin increased cell viability and reduced the number of apoptotic cells as measured by various assays. Linarin could also inhibit acetylcholinesterase activity.
“These results suggest that linarin prevents neurotoxicity and raise the possibility that linarin may be a potent therapeutic compound against Alzheimer’s disease acting through both acetylcholinesterase inhibition and neuroprotection.“
See this article on Mint antioxidant activity