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Role of phenolic compounds in peptic ulcer: An overview

November 8, 2011

Peptic ulcer is the most common gastrointestinal tract (GIT) disorder in clinical practice, which affects approximately 5-10% of the people during their life. The use of herbal drugs for the prevention and treatment of various diseases is constantly developing throughout the world.  Phenolic compounds have attracted special attention due to their health-promoting characteristics.

Many studies have been carried out that strongly support the contribution of polyphenols to the prevention of cardiovascular diseases, cancer, osteoporosis, neurodegenerative diseases, and diabetes mellitus, and suggest a role in the prevention of peptic ulcer.

Polyphenols can display medicinal in the GIT area, acting as anti-secretory, cytoprotective, and antioxidant agents.

In this review by Sumbul et al  summarise the literature on some potent antiulcer plants, such as, Oroxylum indicum, Zingiber officinale, Olea europaea L., containing phenolic compounds, such as, baicalein, cinnamic acid, oleuropein, rutin, quercetin, and tephrosin, as active ingredients.

Calm&Relax: ingredients containing Quercetin and similar active compounds

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