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Turmeric: Potential Gastro-intestinal and Cancer Treatment

December 5, 2011

Irving et al, studied Curcumin a naturally occurring phytochemical and an extract of Turmeric and show potential for gastro-intestinal and cancer treatments.

In vitro and in vivo data have paved the way for curcumin to become the subject of clinical trials. Curcumin modulates key signalling pathways important in cellular processes. Numerous mechanisms of action have been elucidated.

Curcumin has potent anti-inflammatory and anticarcinogenic properties and early-phase trials have shown pharmacological properties and consistently demonstrate it to be safe and well tolerated.  Evidence of efficacy has been derived from animal models or small clinical trials. There is only finite data supporting the use of curcumin in phase III trials with specific diseases (e.g. ulcerative colitis). However, for the vast majority of conditions additional early-phase studies are required to justify larger trials determining efficacy.

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