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Natural Ingredients and Immunity

February 22, 2012

There is a lot to be said for eating healthily and exercising well – both seem to help with our immunity.  Herbal remedies can also help and below is a quick summary of several key InnOrbit ingredients which are implicated in improving the immune function and just may help to stave off colds and flu as part of a healthy lifestyle:

Green Tea

Green Tea Benefits have been demonstrated with Epigallocatechin gallate (EGCG), a bioactive component of green tea. Researchers investigated whether EGCG affected CD11b expressed on B cells, similar to cytotoxic T cells. The effects of EGCG on the ability of B cells to adhere to and to transmigrate through the endothelial cell layer were evaluated.  EGCG has a strong suppressive activity on the adhesive and migratory abilities of peripheral blood B cells. This suppressive activity was mediated by the binding of EGCG to CD11b on B cells. B cell plays an important role in the humoral immunity and therefore EGCG could be a promising drug for the prevention and/or treatment of allergic and/or autoimmune diseases. Check out too this Review Article on Green Tea.

Green tea and Ayurvedic Herbs 

Data from two studies indicated that regular consumption of the tea fortified with Ayurvedic herbs enhanced NK cell activity, which is an important aspect of the (early) innate immune response to infections.

Pennywort (Centella asiatica)

Centella asiatica extracts on cell-mediated and humoral immune responses was studied by Punturee et al.  Their results reveal that there is an immuno-modulating activity of Centella extracts with regard to both non-specific cellular and humoral immune responses.  The data available suggest that they may have chemopreventive or anticancer potential.

Similarly, the immunomodulatory activity of extracts of  C. asiatica was evaluated.  For C.asiatica, significant increases in the phagocytic index and total WBC count were observed and the F ratio of the phagocytic index was also significant.

Cinnamon

Results suggest that Cinnamon Extracts can affect immune responses by regulating anti- and proinflammatory and GLUT gene expression.

Licorice / Liquorice (Glycyrrhiza glabra)

The immune and antioxidant activities of Glycyrrhiza glabra (Liquorice) polysaccharides were studied in an animal model.

Results suggest that Liquorice compounds significantly enhanced immune and antioxidant enzyme activities concluding that these compounds treatment can enhance immune activities, and reduce oxidative stress.

Ginger

Ginger extract inhibits macrophage activation and APC function and indirectly inhibits T cell activation thereby potentially positively influencing immunity.

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