Ginger constituents show Neuro-Protective properties
6-Shogaol, a ginger constituent, modulates neuroinflammation and could protect the brain. Ha et al, writing in the Journal of Neuropharmacology (Mar 23, 2012) studied processes deleterious to neurons, which can result in neurodegeneration.
Inhibition of certain mechanisms, like microglial activation, could be a useful strategy in searching for neuroprotective agents.
Microglia are a type of cell of the brain and spinal cord which act as the main form of active immune defense in the central nervous system (CNS).
The effects of 6-shogaol, a phytochemical from Ginger (Zingiber officinale) showed significant neuroprotective effects in vivo in transient global ischemia via the inhibition of microglia. These results suggest that 6-shogaol is an effective therapeutic agent for treating neurodegenerative diseases.