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Green Tea: Virus Protection and Immunity Control

April 13, 2012

Chen et al (Archives of virology, Apr 11, 2012) showed that Green Tea Epigallocatechin-3-gallate (EGCG) inhibits the replication cycle of a virus (hepatitis C)

The inhibitory mechanisms of EGCG were attributable to the suppression of both the virus entry and RNA replication steps. Furthermore, the virus could be rapidly eliminated from cells. These data indicate that EGCG is a potential candidate as a preventive and antiviral drug for viruses – in this case Hepatitis C infection.

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Also, Chen was part of  a team led by Ku that investigated the pathways involved in epigallocatechin gallate (EGCG) modulation of insulin-like growth factor (IGF)-I-stimulated and IGF-II-stimulated mitogenesis in 3T3-L1 preadipocytes (forming fat cells and potential immunity function).

Notes:

Preadipocytes are present throughout adult life in adipose tissues and can proliferate and differentiate into mature adipocytes (fat cells) according to the energy balance. An increasing number of reports demonstrate that cells from adipose lineages (preadipocytes and adipocytes) and macrophages share numerous functional or antigenic properties. Recent work has indicated that there is a strong link between Adipose precursors and and the innate immunity processes.

Stop Press: September 2012

Amelioration of influenza virus-induced reactive oxygen species formation by epigallocatechin gallate derived from green tea.  Ling et al

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