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Latest on Liquorice: Bones, Brains and Liver

April 28, 2012

InnOrbit Key natural ingredient Liquorice is in the scientific news again.  Here we summarise the latest research results.

Neuro-Protective Properties

Results suggest that liquorice isolate, isoliquiritigenin, may protect against induced oxidative stress and hippocampal neuronal cell death.  The research results suggest that this liquorice component could be useful in the development of drugs to prevent or treat neurodegenerative diseases.

Bone Protection

Results indicate that Liquorice component isoliquiritigenin suppresses osteoclastogenesis (degeneration of bone) and inflammatory bone loss. Therefore, this Liquorice component may be considered as a novel therapeutic and/or preventive strategy against bone degenerative diseases.

Liquorice Detoxifying Treatment

Liquorice is used as a detoxifying treament.  Research study results suggest  the regulation of plasma bile acids may be an important evidence to explain this detoxifying mechanism.


Yang et al,  Isoliquiritigenin isolated from Glycyrrhiza uralensis protects neuronal cells against glutamate-induced mitochondrial dysfunction.

Zhu et al, Licorice isoliquiritigenin suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo.

Qiao et al, Metabolic regulatory effects of licorice: A bile acid metabonomic study by liquid chromatography coupled with tandem mass spectrometry.

Liquorice is a key ingredient in:

  • UP&GO: A boost of natural energy.

  • SLIM&FIT: Helps to control and balance your weight.

  • CALM&RELAX: Relax after a hard day and enhance natural sleep.

  • YOUNG&FUN: Helps brain function and complements a full and active life.

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