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Antitumor activity of Green Tea polyphenol

August 18, 2012

A study by Lemarié et al, focussed on thetherapeutic potential of epigallocatechin-3-gallate (EGCG), a Green Tea polyphenol, for its anticancer properties. The aim of this study was to determine whether a tumor-targeted vesicular formulation of EGCG would suppress the growth of carcinoma and melanoma in vitro and in vivo in a model study system.

The intravenous administration of EGCG encapsulated in transferrin-bearing vesicles resulted in tumor suppression in 40% of various tumours. The results suggest that Encapsulation of EGCG in transferrin-bearing vesicles is a promising therapeutic strategy.

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