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Green Tea Extract Improves Learning and Memory Deficits in a model system

August 25, 2012

Ischemic stroke occurs when an artery to the brain is blocked. The brain depends on its arteries to bring fresh blood from the heart and lungs. The blood carries oxygen and nutrients to the brain, and takes away carbon dioxide and cellular waste. If an artery is blocked, the brain cells (neurons) cannot make enough energy and will eventually stop working. If the artery remains blocked for more than a few minutes, the brain cells may die. This is why immediate medical treatment is critical.


Ischemic stroke may result in brain damage and behavioral deficits including memory impairment.


The protective effects of Green Tea extract and its major functional polyphenol (-)-epigallocatechin gallate (EGCG) on memory were examined by Wu et al, in a cerebral ischemic animal model system.


Green Tea extract and EGCG significantly improved ishemic-induced memory impairment in a Morris water maze test. Various marker compounds like Malondialdehyde levels were increased by long-term treatment with Green Tea extract and EGCG.


Green Tea extract and its active polyphenol EGCG were shown to improve learning and memory deficits in a cerebral ischemia animal model and such protection may be due to the reduction of oxidative stress and neuroinflammation.

Scientific American: The Power of the Memory Molecule

Green Tea is a base used in The Wise Herb Company range of infusions.

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