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Neem Anticancer Properties: Induces Apoptosis and Autophagy in Cancer cells

August 25, 2012

Azadirachta indica, also known as Neem, has a wide range of functional health properties as we have seen on this website in previous reports.

 

Neem extracts and its purified products were studied by Srivastava et al and examined (& reported in Carcinogenesis) for induction of apoptosis in multiple cancer cell types.

 

The researchers have shown that Neem extracts contain components like neem limonoids including azadirachtin which can induce apoptotic and autophagic cell death – effectively stopping cancer proliferation.

 

In conclusion, the results of this study demonstrate for the first time, that Neem induces caspase-dependent and AIF-mediated apoptosis, and autophagy in cancer cells.

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