Green Tea & Anti-Cancer Effects: Latest Research
There are numerous papers recently published which attribute Green Tea polyphenols to some anti-Cancer effect. Green tea catechins (like (-)-Epigallocatechin-3-gallate) are known to function as anticancer agents via inhibition of carcinogenesis during the initiation, promotion and progression stages. Many potential mechanisms have been proposed. Although we don’t propose taking Green Tea will cure cancer, and our infusions are not designed to cure any illness, the information below suggests that there could be a bonus over and above what we are proposing in terms of a health functionality with our natural infusions.
Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates vasculogenesis and angiogenesis. VEGF’s normal function is to create new blood vessels during cancer proliferation. The inhibition of VEGF by EGCG was associated with suppression of neuropilin a protein receptor associated with cancer (Shankar et al). EGCG also inhibited several other factors.
These data suggest that EGCG inhibits pancreatic cancer tumor growth, angiogenesis, and metastasis. In conclusion, the investigators suggest that EGCG can be used for the prevention and/or treatment of pancreatic cancer.
The precise mechanism of lung cancer prevention by green tea catechins remains unsure.
MicroRNAs (miRs) are a class of nucleotide small non-coding RNAs and play critical roles throughout cellular development and regulation including cancer development. New evidence found by Zhong et al demonstrates that tea catechins influence the expression of miRs in human cancer cells to inhibit tumorigenesis. Results suggest that green tea catechins mediate the inhibition of proliferation of lung cancer cells through the a specific signaling pathway.
Human endometrial cancer:
Results from a study by Manohar et al suggest that Green Tea EGCG inhibits cellular proliferation via inhibiting various pathways and can inducing apoptosis via Reactive Oxygen Species generation and activation of various biochemical agents in endometrial carcinoma cells.