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Ginger and Effects on Melanin Content & Potentially Vitamin D

November 13, 2012

The effects of shogaol, a key bioactive ingredient of ginger, on melanogenesis was studied by Yao et al in an animal model system.

Melanogenesis: The formation of melanin by living cells. There can be benefits to having a low level of melanogenesis. High levels of melanin interfere with the absorption of UV rays necessary for the production of important compounds such as Vitamin D. Low levels of Vitamin D can result in an array of different problems.

Treatment of the cells with [6]-shogaol reduced the melanin content in a concentration-dependent manner.

The results indicate that [6]-shogaol inhibits melanogenesis in melanoma cells via activating the ERK pathway.

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