Ginger and Effects on Melanin Content & Potentially Vitamin D
The effects of shogaol, a key bioactive ingredient of ginger, on melanogenesis was studied by Yao et al in an animal model system.
Melanogenesis: The formation of melanin by living cells. There can be benefits to having a low level of melanogenesis. High levels of melanin interfere with the absorption of UV rays necessary for the production of important compounds such as Vitamin D. Low levels of Vitamin D can result in an array of different problems.
Treatment of the cells with -shogaol reduced the melanin content in a concentration-dependent manner.
The results indicate that -shogaol inhibits melanogenesis in melanoma cells via activating the ERK pathway.