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Components of Herbal Medicines and Their Pharmacological Activities in Diabetes and Diabetic Complications

December 9, 2012

Alqahtani et al, from the University of Sydney, studied Pentacyclic triterpenoids – compounds found in various herbal plants like Glycyrrhiza species (Liquorice), Centella asiatica, Camellia sinensis (Green Tea) amongst others. These plants are used in traditional medicines like Ayurveda and are known to be effecient in the treatment of diabetes and diabetic complications.



A large number of bioactive pentacyclic triterpenoids, such as oleanolic acid, glycyrrhizin, glycyrrhetinic acid, ursolic acid, betulin, betulinic acid and lupeol have shown multiple biological activities with apparent effects on glucose absorption, glucose uptake, insulin secretion, diabetic vascular dysfunction, retinopathy and nephropathy.

In conclusion, the investigators conclude that these compounds, pentacyclic triterpenes, provides a promising approach for diabetes management.

Centella asiatica, Liquorice and Green Tea are key components in the natural recipes used by The Wise Herb Company.


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