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Theanine from Green Tea and Addictive effects of Nicotine

December 20, 2012

The inhibitory effect of L-theanine, an amino acid derivative found in Green Tea, was studied (Di et al) in conjunction with the potential addictive effects of nicotine. The investigators also studied the underlying mechanisms of this action.

Green tea can help you quit smoking: Lifestyle Magazine

They found that L-theanine, in an animal model system, inhibited the rewarding effects of nicotine and reduced the excitatory status induced by nicotine.

Further assays indicated that L-theanine significantly inhibited nicotine-induced tyrosine hydroxylase (TH) expression and dopamine production in the animal model and additionally decreased the number of cells that could react to nicotine.

In conculsion this study suggests that L-theanine reduces the nicotine-induced reward effects via inhibition of the dopamine reward pathway. Green Tea derivatives and products may offer new therapeutic strategies for treatment of tobacco addiction.

Green Tea

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