Anticancer Activity of Amla (emblica – Indian Gooseberry) in Cervical Cancer Cells
Amla is a plant traditionally consumed for its significant nutritive and medicinal values in many cultures.
The mechanisms by which it works was further elucidated by Mahata et al in human cell lines.
The scientists from the Institute of Cytology and Preventive Oncology (Pradesh) investigated mechanism of action of P. emblica fruit extract by studying its effect on various ‘biomarkers’ that are essential for tumorigenicity of cervical cancer cells.
The results showed a dose-and time-dependent inhibition of DNA binding activity of constitutively active AP-1 in both HPV16-positive (SiHa) and HPV18-positive (HeLa) cervical cancer cells.
In conclusion, these results suggest that Amla (P. emblica) exhibits anticancer activity indicating its possible utility for treatment of human papillomavirus HPV-induced cervical cancers.
Amla is a key ingredient in the handcrafted green tea herbal infusions of The Wise Herb Company.