Skip to content

Epigallocatechin-3-gallate from Green Tea attenuates head and neck cancer

July 30, 2013

Green Tea

Many head and neck cancers are believed to be initiated from and maintained by cancer stem cells. In a study by Lee et al, Epigallocatechin-3-gallate (EGCG), the most abundant polyphenol in green tea, was shown to inhibit cancer growth and induce apoptosis in various cancers, including head and neck cancers.

The investigators examined the anti-tumour effect of Green Tea EGCG on the above cancers to elucidate further its mechanism.

 Green TEA

The studies indicated that EGCG inhibits the self-renewal capacity of head and neck squamous cancers by suppressing their sphere forming capacity, and attenuates the expression of stem cell markers.

Green Tea is a key ingredient in the herbal infusions hand crafted by The Wise Herb Company.

EGCG treatment was shown to augment cisplatin-mediated chemosensitivity.

Green-Tea-Field

The data suggest that EGCG in combination with cisplatin can be used for the management of the above types of cancers.

See also: Green tea exhibits inhibitory effects on different stages of tumorigenesis

No comments yet

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: