Liquorice (licorice) has been used in traditional medicines like Ayurveda for treatment of many diseases, including inflammations and immunological disorders.
Studies by Fu et al suggest that the anti-inflammatory and immunomodulation activities of liquorice are due to its active component, glycyrretinic acid (GA). They suggest a potential mechnism for these positive health effects.
Their results suggest that GA blocks Kv1.3 channels, which probably helps to explain its anti-inflammatory and immunomodulation effects.
The handcrafted recipe of up & go contains liquorice which helps with energising your day and helping with strengthening immunity.
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Atherosclerosis — hardening and narrowing of the arteries — is a progressive process that silently and slowly blocks arteries, putting blood flow at risk.
Gingerol, a component of Ginger, is under investigation for a variety of therapeutic uses. The initiating step in atherosclerosis is proteoglycan synthesis leading to increased binding of low-density lipoproteins. TGF-β facilitates this process. Kamata et al evaluated the effects of (S)--gingerol on these TGF-β-mediated proteoglycan changes to explore its potential as an anti-atherosclerotic agent.
Ginger is a key herbal component in The Wise Herb Company handcrafted recipes.
Ginger has anti-hyperactivity and anti-inflammation on airways. Ginger has always had a special value for helping people to clear their airways or stave off the symptoms of colds etc.
A study Mangprayool et al investigated the bronchodilatory activity of ginger oil and identified its active compound.
A bronchodilator is a substance that dilates the bronchi and bronchioles, decreasing resistance in the respiratory airway and increasing airflow to the lungs. Bronchodilators may be endogenous (originating naturally within the body), or they may be medicinal administered for the treatment of breathing difficulties. They are most useful in obstructive lung diseases, of which asthma and chronic obstructive pulmonary disease are the most common conditions.
Citral, eucalyptol and camphene were found to be the major components of Ginger oil.
The animal study provides the pharmacological basis supporting the therapeutic potential of Z. officinale (Ginger) as a bronchodilator.
Amla is a plant traditionally consumed for its significant nutritive and medicinal values in many cultures.
The mechanisms by which it works was further elucidated by Mahata et al in human cell lines.
The scientists from the Institute of Cytology and Preventive Oncology (Pradesh) investigated mechanism of action of P. emblica fruit extract by studying its effect on various ‘biomarkers’ that are essential for tumorigenicity of cervical cancer cells.
The results showed a dose-and time-dependent inhibition of DNA binding activity of constitutively active AP-1 in both HPV16-positive (SiHa) and HPV18-positive (HeLa) cervical cancer cells.
In conclusion, these results suggest that Amla (P. emblica) exhibits anticancer activity indicating its possible utility for treatment of human papillomavirus HPV-induced cervical cancers.
Amla is a key ingredient in the handcrafted green tea herbal infusions of The Wise Herb Company.
Scientific studies have shown that Holy Basil or Tulsi possesses antiinflammatory, analgesic, antipyretic, antidiabetic, hepatoprotective, hypolipidemic, antistress, and immunomodulatory activities. Studies have also shown that Tulsi and some of its phytochemicals eugenol, rosmarinic acid, apigenin, myretenal, luteolin, β-sitosterol, and carnosic acid prevented chemical-induced skin, liver, oral, and lung cancers and to mediate these effects by increasing the antioxidant activity, altering the gene expressions, inducing apoptosis, and inhibiting angiogenesis and metastasis.
The aqueous extract of Tulsi and its flavanoids, orintin, and vicenin are shown to protect against γ-radiation-induced sickness and mortality and to selectively protect the normal tissues against the tumoricidal effects of radiation (animal studies). The other important phytochemicals like eugenol, rosmarinic acid, apigenin, and carnosic acid are also shown to prevent radiation-induced DNA damage.
A review by Baliga et al summarises the results related to the chemopreventive and radioprotective properties of Tulsi and also emphasizes aspects that warrant future research to establish its activity and utility in cancer prevention and treatment.
Holy Basil (Tulsi)Ocimum sanctum is a key ingredient of the herbal Green Tea infusions hand-crafted by the Wise Herb Company.